germ line mutation वाक्य
"germ line mutation" हिंदी में germ line mutation in a sentenceउदाहरण वाक्य
- It also greatly improved yields in germ line mutations.
- Germ line mutations in DNA repair genes cause only 2 5 % of colon cancer cases.
- These germ line mutations are indicated in a box at the left of the figure with an arrow indicating their contribution to DNA repair deficiency.
- For instance two dominant-negative germ line mutations were identified in the Ataxia telangiectasia mutated ( ATM ) gene which increases susceptibility to breast cancer.
- Some germ line mutations in DNA repair genes cause up to 100 % lifetime chance of cancer ( e . g ., p53 mutations ).
- Such germ line mutations are shown in a box at the left of the figure, with an indication of their contribution to DNA repair deficiency.
- Individuals with a germ line mutation causing deficiency in any of 34 DNA repair genes ( see article DNA repair-deficiency disorder ) are at increased risk of cancer.
- These mutations, which are identical to the ones present in SGS as germ line mutations, impair the degradation of SETBP1 and therefore cause increased cellular levels of the protein.
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